The Histone H1.4(Thr18) Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to H1.4 linker histone, cluster member. This antibody recognizes Mouse, and Rat antigen. The Histone H1.4(Thr18) Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity)